As a blogger, I recently researched how long Baclofen stays in our system. Baclofen, a muscle relaxant and antispastic medication, typically takes about 3-4 hours for its effects to peak. It has a half-life of approximately 3-4 hours, meaning that it takes this long for half of the drug to leave your system. Therefore, it may take around 15-20 hours for the drug to be completely eliminated from our body. However, factors like age, kidney function, and dosage can influence how long Baclofen stays in one's system.